Published02 May Abstract Introduction. The stem bark of Maerua angolensis DC. Capparaceae is traditionally used for management of epilepsy. Our aim was to evaluate the antiseizure potential and identify possible mechanisms by which the effects are registered. Rats were observed for latency to and duration of myoclonic seizures and additionally the level of protection against oxidant markers and products was assessed in vitro and in vivo. In addition, the extract protects against the generation of free radicals and the oxidative products of the PTZ-induced seizures.
|Published (Last):||18 January 2017|
|PDF File Size:||6.91 Mb|
|ePub File Size:||19.49 Mb|
|Price:||Free* [*Free Regsitration Required]|
Description[ edit ] The tree has a rounded crown and smooth grey bark flaking to reveal yellowish-orange patches. As with most species in the family the twigs and branches display prominent lenticels. Leaves are soft and drooping, with petioles equal to the leaves in length, and visibly thicker or inspissate at their extremities.
Leaves are alternate and broadly elliptic to ovate, with rounded or notched apex and a terminal bristle mucronate. Leaf surfaces are often noticeably scratched by their rubbing against the bristles of surrounding leaves. The species is variable as regards pubescence, ranging from entirely glabrous to pubescent on stems and leaves. The fragrant, pincushion-like flowers are without petals and are produced in abundance at the beginning of the rainy season.
Filaments are numerous c. The 4 calyx segments recurve on opening, and the base is fringed with hairs. The distinctive torulose fruit is a silique and resembles a string of beads some mm in length. A slender, taller version of this species growing in the Socotra archipelago, Somalia , Ethiopia and Yemen has been named Maerua angolensis subsp.
Uses[ edit ] Despite their unpleasant, bitter taste, the leaves are used by African rural tribes during famine periods as a food supplement, and also used as a purgative.
Decoctions of the leaves are given to children suffering amoebic dysentery or jaundice , and to treat rheumatism, stomach-ache, epilepsy and diarrhoea, while decoctions of the bark are used to treat malaria and as an aphrodisiac. Game and livestock readily browse the foliage.
Instar larvae may defoliate a tree completely, but leaves regrow readily. Further studies suggested that the bark is non-toxic in anti-inflammatory doses, supporting ethnomedical use of the plant in managing inflammation.
MAERUA ANGOLENSIS PDF
Sildenafil was obtained from Pfizer Inc. Filaments are numerous c. In other projects Wikimedia Commons. Evidence-Based Complementary and Alternative Medicine The GABAergic mediation of antiseizure activity is in agreement with earlier studies carried out with the ethanolic fraction of the stem bark [ 20 ].