Definition NCI A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids cortisolmineralocorticoids aldosterone, deoxycorticosteroneand androgens dehydroepiandrosterone to meet physiologic needs, despite release of ACTH from the pituitary. Besnier-Boeck-Schaumann maladie de BC: Prolonged treatment of patients with high doses of inhaled corticosteroids may result in adrenal suppression and acute adrenal crisis. Tachycardie Ventriculaire Soutenue U [ modifier modifier le wikicode ] U: We assume no liability for the accuracy, completeness or timeliness of this information. To add entries to your own vocabularybecome a member of Reverso community or login if you are already a member.
|Published (Last):||27 September 2005|
|PDF File Size:||7.38 Mb|
|ePub File Size:||19.19 Mb|
|Price:||Free* [*Free Regsitration Required]|
Hypoglycemic seizures or symptoms of dehydration are common manifestations seen in children. There was a problem providing the content you requested Immediate treatment in an intensive care unit is necessary. A precipitating illness severe infection, acute myocardial infarction,strokesurgery without adrenal support, pregnancy, any acute or chronic disease, or acute trauma are other potential causes of an acute adrenal crisis.
If untreated, shock and imsuffisance adrenal hemorrhage can rapidly lead to death. AAI may also result from corticotroph insufficiency, either isolated or more often resulting from complete anterior pituitary insufficiency. During this time cardiac monitoring is essential. Disease definition Acute adrenal insufficiency AAI is a rare but severe condition caused by a sudden defective production of adrenal steroids cortisol and aldosterone.
Preventive strategies include dosage increase of steroid hormones during times of stress in those with CPIA. Etiology Steroid withdrawal is the most common cause of AAI in patients with chronic adrenal insufficiency.
Peritonitis is often a differential diagnosis as well as other causes of adrenal destruction such as bilateral adrenalectomy, Waterhouse-Friderichsen syndrome see this termautoimmune adrenalitis, infectious adrenalitis and tumour infiltration. Adrenal destruction may occur in the absence of CPAI history and may aigus due to bilateral massive adrenal hemorrhage BMAH; see this term as seen in Waterhouse-Friderichsen syndrome see this term.
Patients and their families should also be educated on what to do during an adrenal crisis. Other search option s Alphabetical list.
The onset is often sudden. Summary and related texts. Administration of mg hydrocortisone i. Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. Acute adrenal failure Acute adrenocortical insufficiency Addisonian crisis Adrenal crisis Adrenocortical crisis Prevalence: The disease may occur at any age. Diagnostic methods The clinical signs are nonspecific but the diagnosis of AAI is suspected if a patient presents with hypotonia or shock that responds poorly to catecholamines.
It represents an emergency, thus the rapid recognition and prompt therapy are critical for survival even before the diagnosis is made. Steroid withdrawal is the most common cause of AAI in patients with chronic adrenal insufficiency. Antibiotics, vasopressors, heparin, packed red blood cells, platelets, cryoprecipitates and fresh frozen plasma are also administered if needed. Clinical description The disease may occur at any age.
Management and treatment Immediate treatment in an intensive care unit is insuffissance. The initial presentation may be limited to abdominal pain, nausea, vomiting and fever. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis surrenakienne diagnosis or treatment.
Summary Epidemiology Exact prevalence of acute adrenal insufficiency is unknown. Orphanet: Insuffisance surrenalienne aigue Laboratory exams show signs of adrenal insufficiency hypoglycemia, hyponatremia and elevated natriuresis, hyperkaliemia, hemoconcentration, hypochloremic metabolic acidosis and functional renal failure confirmed by hypocortisolemia, increased ACTH, and an insufficient response to rapid ACTH stimulation testing that leads to the diagnosis of absolute and peripheral AAI.
Specialised Social Services Eurordis directory. For all other comments, please send your remarks via contact us. It can also be caused by tuberculosis, opportunistic mycoses and viral infections in immunocompromised patients and adrenal metastases.
Acute adrenal insufficiency AAI is a rare but severe condition caused by a sudden defective production of adrenal steroids cortisol and aldosterone. The clinical signs are nonspecific but the diagnosis of AAI is suspected if a patient presents with insuffjsance or shock aigud responds poorly to catecholamines. Secondary adrenal insufficiency needs to be eliminated. Only comments written in English can be processed.
The documents contained in this web site are presented for information purposes only. Check this box if you wish to receive a copy of your message. Differential diagnosis Secondary adrenal insufficiency needs to be eliminated. Prognosis Prognosis varies depending on the etiologies, but is generally correlated with the rapidity of diagnosis insfufisance medical assistance. Health care resources for this disease Expert centres Diagnostic tests 0 Patient organisations 5 Orphan drug s 4.
Prognosis varies depending on the etiologies, but is generally correlated with the rapidity of diagnosis and medical assistance. In case of anterior pituitary insufficiency, ACTH is low. Related Articles
Insuffisance surrénalienne aigüe
Les symptômes de l'insuffisance surrénalienne aiguë